Hotel Information

San Antonio’River Walk

All educational and conference activities will take place at the Grand Hyatt San Antonio.

Grand Hyatt San Antonio

600 E. Market Street  
San Antonio, Texas

Set amidst a blend of histories and a modern city, this urban retreat has a premier location on the San Antonio River Walk and is within walking distance of the Alamodome, Tower of The Americas and The Alamo.

There are few places more magical than San Antonio’s River Walk; at Grand Hyatt San Antonio, enjoy a stay just steps from this landmark, as well as the Alamo, iconic riverside restaurants, quirky shops, and more. Our luxury San Antonio hotel is in the heart of San Antonio’s historic downtown, making it easy to unwind in your spacious room after a day of exploring.

Grand Hyatt San Antonio

The Grand Hyatt San Antonio is home to spacious rooms, each with views of downtown, contemporary design and luxurious amenities. Relax on plush Hyatt Grand Beds™ topped with luxury linens, enjoy generous work spaces and marvel at the natural stone bathrooms.

We look forward to welcoming you to San Antonio!

It has come to our attention that some convention and expo housing agencies are actively contacting exhibitors and soliciting hotel reservations for the 2019 Healthcare Systems Process Improvement Conference.

The official conference hotel with guaranteed rates are listed on this website. If you provide your credit card information to any unauthorized agencies/websites, your card may be charged but you may not have a reservation.

Please be advised that IISE is not providing these companies with any of your information and they are not affiliated with IISE in any way. The official conference hotels with reservation information will be posted on this website.


The Grand Hyatt San Antonio is offering HSPI attendees the discounted rate of $219.00 - Single/Double Occupancy. Rates are subject to the appropriate state, local, and any occupancy taxes. These taxes are currently 8.25% Sales Tax and 8.5% Occupancy Tax (16.75%).

The room block will be available until Jan. 29, 2019, 4 p.m. CST, or until the block is sold out.

Check-in time: 4 p.m.

Check-out time: 11 a.m.

Make your reservations now before the block is sold out.



Delta Air Lines is pleased to offer special discounts for Healthcare Systems Process Improvement Conference attendees!

Please click here to book your flights!

You may also call Delta Meeting Network® at 1.800.328.1111* Monday–Friday, 7:00 a.m. – 7:30 p.m. (CT) and refer to Meeting Event Code NMSLW.

*Please note there is not a service fee for reservations booked and ticketed via our reservation 800 number.

Childcare Services

HSPI Conference attendees who wish to obtain the services of childcare professionals during the meeting may contact North Side Sitters Club, a service recommended by the Grand Hyatt San Antonio, our headquarters hotel.

You can contact North Side Sitters Club at 210.710.7940, or by visiting their website.